I increased my dose from 1x per day to 3 for a breast cancer diagnosis and the cancer marker dropped more than 1/2 in 4-5 months. (I was also taking an estrogen blocker for estrogen driven breast cancer.). I also noticed after a month or so that my stiff, achy hip was no longer stiff or achy! I was especially happy about this because a side effect of the estrogen blocker is painful achy joints. I would recommend this product for anyone who is fighting cancer or another chronic illness at 3 x a day.